From Arizona to Maine to North Carolina, millions of Americans are not just bracing, but preparing for what could be a devastating winter storm.

A major, widespread winter storm will hammer the parts of the South, Midwest and Northeast Friday through Monday with potentially damaging ice and heavy snow for millions from New Mexico and Texas to parts of New England.

Shoveling snow, especially the heavy, wet kind, can strain the heart and body and trigger serious health risks.

The South needs to be on guard this week as a storm could bring a potentially dangerous situation for millions this weekend.